Summary
The paper is to discuss the role of the non structural protein 1 also known as NSP1 which is found among the rotavirus as it is known to be responsible in the blockage of interferon also known as IFN. This is done through signaling during the meditation of the proteasome-dependent degradation found with the IFN-regulatory factors which are referred to as IRFs. This is also called the β-transducin where there is a repeat of elements which contain the proteins where it will be known as β-TrCP. The paper will also highlight some of the ways in which the NSP1 can subvert some of the innate immune responses through various mechanisms.